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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVEN
All Species:
4.55
Human Site:
S261
Identified Species:
12.5
UniProt:
Q9NQS1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQS1
NP_065104.1
362
38506
S261
L
L
G
K
D
N
P
S
P
G
P
S
R
D
S
Chimpanzee
Pan troglodytes
XP_510277
445
47597
S344
L
L
G
K
D
N
P
S
P
G
P
S
R
D
S
Rhesus Macaque
Macaca mulatta
XP_001085261
356
37974
R255
L
L
G
T
D
N
P
R
P
G
P
S
T
D
S
Dog
Lupus familis
XP_535418
366
40454
C266
E
L
K
P
A
A
C
C
P
A
P
S
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9K3
342
37176
R241
S
L
G
R
G
S
L
R
Q
S
P
L
E
G
L
Rat
Rattus norvegicus
NP_001101227
217
23887
A134
S
S
P
P
Q
S
A
A
D
H
L
E
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001005791
352
38620
V254
P
G
S
K
R
G
P
V
T
S
A
A
E
P
F
Frog
Xenopus laevis
NP_001090621
299
33207
R214
E
T
A
L
P
Q
E
R
V
L
N
A
T
K
A
Zebra Danio
Brachydanio rerio
NP_001038757
322
36092
I234
S
V
S
I
S
T
T
I
P
P
D
D
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.3
93.3
60.9
N.A.
71.5
41.7
N.A.
N.A.
48.6
40.8
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.7
95.8
68.5
N.A.
79
48.6
N.A.
N.A.
56.3
52.4
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
26.6
N.A.
20
0
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
26.6
N.A.
33.3
20
N.A.
N.A.
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
12
12
12
0
12
12
23
0
0
12
% A
% Cys:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
0
12
0
12
12
12
34
12
% D
% Glu:
23
0
0
0
0
0
12
0
0
0
0
12
34
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
45
0
12
12
0
0
0
34
0
0
12
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
34
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
34
56
0
12
0
0
12
0
0
12
12
12
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
34
0
0
0
0
12
0
0
0
0
% N
% Pro:
12
0
12
23
12
0
45
0
56
12
56
0
0
12
12
% P
% Gln:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
12
0
0
34
0
0
0
0
23
0
0
% R
% Ser:
34
12
23
0
12
23
0
23
0
23
0
45
0
0
34
% S
% Thr:
0
12
0
12
0
12
12
0
12
0
0
0
23
0
0
% T
% Val:
0
12
0
0
0
0
0
12
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _